Mouse Monoclonal Antibody to TIE1
货号：
30619
别名：
TIE; JTK14
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P35590
规格：
目录价
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Description |
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This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
References |
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| 1. Int J Oncol. 2007 Oct;31(4):893-7. 2. Cancer. 2002 Mar 1;94(5):1517-21. |
Specification |
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| Aliases | TIE; JTK14 |
| Entrez GeneID | 7075 |
| Swissprot | P35590 |
| clone | 8D12D2 |
| WB Predicted band size | 125kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| IHC | 1/200 - 1/1000 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using TIE1 mouse mAb against HepG2 cell lysate.
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Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using TIE1 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human kidney tissues using TIE1 mouse mAb with DAB staining.
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