Mouse Monoclonal Antibody to KHDRBS2
货号：
30638
别名：
SLM1; SLM-1; bA535F17.1
应用：
WB,IHC,FCM
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q5VWX1
规格：
目录价
在线咨询
Description |
|---|
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity) |
References |
|---|
| 1. Mol Biol Cell. 2003 Jan;14(1):274-87. 2. |
Specification |
|
|---|---|
| Aliases | SLM1; SLM-1; bA535F17.1 |
| Entrez GeneID | 202559 |
| Swissprot | Q5VWX1 |
| clone | 7G8C10 |
| WB Predicted band size | 39kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Purified recombinant fragment of human KHDRBS2 (AA: 160-349) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
-
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
-
Western blot analysis using KHDRBS2 mouse mAb against K562 (1), HEK293 (2), NTERA-2 (3), Hela (4), HepG2 (5), Jurkat (6), A431 (7), NIH/3T3 (8) cell lysate.
-
Flow cytometric analysis of K562 cells using KHDRBS2 mouse mAb (green) and negative control (red).
-
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using KHDRBS2 mouse mAb with DAB staining.
-
Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using KHDRBS2 mouse mAb with DAB staining.
鄂公网安备42018502007531号
