Mouse Monoclonal Antibody to EPCAM
货号：
30630
别名：
ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1
应用：
WB,IHC,FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P16422
规格：
目录价
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Description |
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This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. |
References |
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| 1. BMC Cancer. 2012 Oct 30;12:501. 2. Am J Surg Pathol. 2012 Dec;36(12):1809-16. |
Specification |
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| Aliases | ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1 |
| Entrez GeneID | 4072 |
| Swissprot | P16422 |
| clone | 7B5C10 |
| WB Predicted band size | 35kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Purified recombinant fragment of human EPCAM (AA: 24-265) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using EPCAM mouse mAb against A431 (1), MCF-7 (2) cell lysate.
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Western blot analysis using EPCAM mouse mAb against PC-12 cell lysate.
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Flow cytometric analysis of A431 cells using EPCAM mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using EPCAM mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using EPCAM mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded Mouse colon using EPCAM mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded Rat stomach(A)Rat kidney(B)Rat colon(C)Rat thyroid(D)Rat bladder(E) using EPCAM mouse mAb with DAB staining.
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