Mouse Monoclonal Antibody to DSG3
货号：
30627
别名：
PVA; CDHF6
应用：
WB,IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P32926
规格：
目录价
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Description |
|---|
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. |
References |
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| 1. J Dermatol Sci. 2012 Feb;65(2):102-9. 2. Am J Pathol. 2009 May;174(5):1629-37. |
Specification |
|
|---|---|
| Aliases | PVA; CDHF6 |
| Entrez GeneID | 1830 |
| Swissprot | P32926 |
| clone | 6G2C11 |
| WB Predicted band size | 107.5kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human DSG3 (AA: 55-159) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using DSG3 mouse mAb against A431 cell lysate.
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Flow cytometric analysis of A431 cells using DSG3 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using DSG3 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human esophageal tissues using DSG3 mouse mAb with DAB staining.
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