Mouse Monoclonal Antibody to BACE1
货号：
30625
别名：
ASP2; BACE; HSPC104
应用：
WB,IF,FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P56817
规格：
目录价
在线咨询
Description |
|---|
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. |
References |
|---|
| 1. J Neurochem. 2012 Jan;120 Suppl 1:62-70. 2. Eur J Neurosci. 2010 Oct;32(7):1223-38. |
Specification |
|
|---|---|
| Aliases | ASP2; BACE; HSPC104 |
| Entrez GeneID | 23621 |
| Swissprot | P56817 |
| clone | 3C1C3 |
| WB Predicted band size | 55.7kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
-
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
-
Western blot analysis using BACE1 mouse mAb against Hela (1), SK-N-SH (2), HepG2 (3), C6 (4), PC-12 (5), PANC-1 (6), NIH/3T3 (7) cell lysate.
-
Immunofluorescence analysis of MCF-7 cells using BACE1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
-
Flow cytometric analysis of Hela cells using BACE1 mouse mAb (green) and negative control (red).
鄂公网安备42018502007531号
