Mouse Monoclonal Antibody to PDK2
货号：
30655
别名：
PDHK2; PDKII
应用：
IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q15119
规格：
目录价
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Description |
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This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
References |
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| 1. Biochemistry. 2008 Feb 26;47(8):2298-311. 2. J Biol Chem. 2006 May 5;281(18):12568-79. |
Specification |
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|---|---|
| Aliases | PDHK2; PDKII |
| Entrez GeneID | 5164 |
| Swissprot | Q15119 |
| clone | 3F2C4 |
| WB Predicted band size | 46.2kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human PDK2 (AA: 178-404) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Immunofluorescence analysis of Hela cells using PDK2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of Hela cells using PDK2 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using PDK2 mouse mAb with DAB staining.
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