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Rabbit Monoclonal to Bcl-XL
货号: P17024
别名: Apoptosis regulator Bcl-X; BLC2L; Bcl-2-like 1 protein bclxl; BCL2L; BCL2L1; BCLX;;Bcl 2 L1
应用: WB,IHC/IHF,IF,IP,FCM
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q07817
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Description

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

Specification

Aliases Apoptosis regulator Bcl-X; BLC2L; Bcl-2-like 1 protein bclxl; BCL2L; BCL2L1; BCLX;;Bcl 2 L1
Swissprot Q07817
WB Predicted band size 26 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human Bcl 2 L1
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
FCM 1/20-1/100
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