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Rabbit Monoclonal to RNF20
货号: P17013
别名: BRE1-A; hBRE1; RING finger protein 20; E3 ubiquitin-protein ligase BRE1A; RNF20; ;RNF20
应用: WB,IF,IP,FCM
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q5VTR2
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Description

Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation.

Specification

Aliases BRE1-A; hBRE1; RING finger protein 20; E3 ubiquitin-protein ligase BRE1A; RNF20; ;RNF20
Swissprot Q5VTR2
WB Predicted band size 114 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen A synthesized peptide derived from human RNF20
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
IF 1/50-1/200
FCM 1/20-1/100
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