Rabbit Monoclonal to Phospho-PP2A alpha(Y307)
货号：
P17029
别名：
eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786;p-PP2A alpha (Y307)
应用：
WB,IHC/IHF,IF,IP
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P67775
规格：
目录价
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Description |
|---|
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
Specification |
|
|---|---|
| Aliases | eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786;p-PP2A alpha (Y307) |
| Swissprot | P67775 |
| WB Predicted band size | Calculated MW: 36 kDa ; Observed MW: 35 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human PP2A alpha around the phosphorylation site of S307 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
| IF | 1/50-1/200 |
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