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Rabbit Monoclonal to Phospho-LAT(Y191)
货号: P17027
别名: 36 kDa phospho-tyrosine adaptor protein; LAT1; lat; pp36;p-LAT (Y220)
应用: WB,IHC/IHF,IF,IP
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P13861
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Description

Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.

Specification

Aliases 36 kDa phospho-tyrosine adaptor protein; LAT1; lat; pp36;p-LAT (Y220)
Swissprot P13861
WB Predicted band size Calculated MW: 28 kDa ; Observed MW: 38 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human LAT around the phosphorylation site of Y220
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
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