Rabbit Monoclonal to Smad2
货号:
P17046
别名:
JV18-1; MADH2; MADR2; Mad-related protein 2; Mothers against DPP homolog 2; Smad 2;;SMAD2
应用:
WB,IF,FCM
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q15796
规格:
目录价
在线咨询
Description |
---|
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells (By similarity). |
Specification |
|
---|---|
Aliases | JV18-1; MADH2; MADR2; Mad-related protein 2; Mothers against DPP homolog 2; Smad 2;;SMAD2 |
Swissprot | Q15796 |
WB Predicted band size | Calculated MW: 52 kDa ; Observed MW: 58 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human SMAD2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/1000-1/2000 |
IF | 1/50-1/200 |
FCM | 1/20-1/100 |
Product Image
-
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
-
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
-
Western blot analysis of Smad2 expression in (1) Jurkat cell lysate;(2) RAW264.7 cell lysate.
-
Immunofluorescent analysis of Hela cells, using Smad2 Antibody.