Rabbit Monoclonal to STAT1
货号：
P17097
别名：
Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84;ISGF3; CANDF7; STAT 1; Stat1;;STAT1
应用：
WB;IP;FCM
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P42224
规格：
目录价
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Description |
|---|
Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. |
Specification |
|
|---|---|
| Aliases | Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84;ISGF3; CANDF7; STAT 1; Stat1;;STAT1 |
| Swissprot | P42224 |
| WB Predicted band size | Calculated MW: 87 kDa ; Observed MW: 84 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | A synthesized peptide derived from human STAT1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| FCM | 1/20-1/100 |
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