Rabbit Monoclonal to ABCG1
货号:
P17146
别名:
ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1;ABCG1; ABC transporter 8; WHITE1;;ABCG1
应用:
WB,IHC/IHF,IF,
反应种属:
Human,Rat
抗体类型:
Primary antibody
Swissprot:
P45844
规格:
目录价
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Description |
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Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP.The lipid efflux is ALB-dependent .Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol. |
Specification |
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Aliases | ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1;ABCG1; ABC transporter 8; WHITE1;;ABCG1 |
Swissprot | P45844 |
WB Predicted band size | Calculated MW: 76 kDa ; Observed MW: 110 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat |
Immunogen | A synthesized peptide derived from human ABCG1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |