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Rabbit Monoclonal to ABCG1
货号: P17146
别名: ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1;ABCG1; ABC transporter 8; WHITE1;;ABCG1
应用: WB,IHC/IHF,IF,
反应种属: Human,Rat
抗体类型: Primary antibody
Swissprot: P45844
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Description

Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP.The lipid efflux is ALB-dependent .Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol.

Specification

Aliases ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1;ABCG1; ABC transporter 8; WHITE1;;ABCG1
Swissprot P45844
WB Predicted band size Calculated MW: 76 kDa ; Observed MW: 110 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen A synthesized peptide derived from human ABCG1
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
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