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Rabbit Monoclonal to Cathepsin D
货号: P17135
别名: CATD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311;Cathepsin D
应用: WB,IHC/IHF,IF,IP,FCM
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P07339
规格:
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Description

Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Specification

Aliases CATD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311;Cathepsin D
Swissprot P07339
WB Predicted band size Calculated MW: 45 kDa ; Observed MW: 46,28 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human Cathepsin D
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
FCM 1/20-1/100
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