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Rabbit Monoclonal to HN1
货号: P17173
别名: ARM2; HN1; HN1A;;JPT1
应用: WB,IF,FCM
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q9UK76
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Description

Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions.

Specification

Aliases ARM2; HN1; HN1A;;JPT1
Swissprot Q9UK76
WB Predicted band size Calculated MW: 16 kDa ; Observed MW: 21 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human JPT1
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IF 1/50-1/200
FCM 1/20-1/100
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