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Rabbit Monoclonal to MLKL
货号: P17219
别名: Mixed lineage kinase domain-like protein; hMLKL; ;MLKL
应用: WB;IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q8NB16
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Description

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage.

Specification

Aliases Mixed lineage kinase domain-like protein; hMLKL; ;MLKL
Swissprot Q8NB16
WB Predicted band size 54 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human MLKL
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC 1/100-1/200
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