Rabbit Monoclonal to MLKL
货号:
P17219
别名:
Mixed lineage kinase domain-like protein; hMLKL; ;MLKL
应用:
WB;IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q8NB16
规格:
目录价
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Description |
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Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. |
Specification |
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Aliases | Mixed lineage kinase domain-like protein; hMLKL; ;MLKL |
Swissprot | Q8NB16 |
WB Predicted band size | 54 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthesized peptide derived from human MLKL |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
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WB | 1/1000-1/2000 |
IHC | 1/100-1/200 |