Rabbit Monoclonal to Caspase 5
货号:
P17331
别名:
CASP5; Apoptosis related cysteine protease; CASP-5; Caspase-5 subunit p10; Protease ICH-3; TY protease;;Caspase 5
应用:
WB,IHC/IHF,IF,IP
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P51878
规格:
目录价
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Description |
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Thiol protease that acts as a mediator of programmed cell death.Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis. |
Specification |
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Aliases | CASP5; Apoptosis related cysteine protease; CASP-5; Caspase-5 subunit p10; Protease ICH-3; TY protease;;Caspase 5 |
Swissprot | P51878 |
WB Predicted band size | Calculated MW: 50 kDa ; Observed MW: 47 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthesized peptide derived from human Caspase 5 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |
IP | 1/20-1/50 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |