Rabbit Monoclonal to Phospho-PKC zeta(T560)
货号：
P17345
别名：
aPKCzeta; nPKC zeta; PKC 2; PKC ZETA; PKCZETA ; Protein kinase C zeta; r14-3-3;;p-PKC zeta (T560)
应用：
WB;IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q05513
规格：
目录价
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Description |
|---|
Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP). Upon lipopolysaccharide (LPS) treatment in macrophages, or following mitogenic stimuli, functions downstream of PI3K to activate MAP2K1/MEK1-MAPK1/ERK2 signaling cascade independently of RAF1 activation. |
Specification |
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|---|---|
| Aliases | aPKCzeta; nPKC zeta; PKC 2; PKC ZETA; PKCZETA ; Protein kinase C zeta; r14-3-3;;p-PKC zeta (T560) |
| Swissprot | Q05513 |
| WB Predicted band size | 68 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human PKC zeta around the phosphorylation site of T560 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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|---|---|
| WB | 1/1000-1/2000 |
| IHC | 1/100-1/200 |
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