Rabbit Monoclonal to Phospho-Smad2(S250)

科研抗体 IVD抗体

货号： P17381

别名： JV18-1, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, Smad 2;;p-SMAD2 (S250)

应用： WB;FCM

反应种属： Human,Mouse,Rat

抗体类型： Primary antibody

Swissprot： Q15796

规格：

100μl 50μl

目录价

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Description
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells (By similarity).

Description

Specification
Aliases	JV18-1, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, Smad 2;;p-SMAD2 (S250)
Swissprot	Q15796
WB Predicted band size	Calculated MW: 52 kDa ; Observed MW: 58 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human SMAD2 around the phosphorylation site of S250
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
FCM	1/20-1/100