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Rabbit Monoclonal to Caspase 14
货号: P17452
别名: CASP14; Caspase-14; Caspase 14; MICE; CASP-14;;Caspase 14
应用: WB,IHC/IHF,IF,IP,FCM
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P31944
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Description

Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum.Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin.In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF.

Specification

Aliases CASP14; Caspase-14; Caspase 14; MICE; CASP-14;;Caspase 14
Swissprot P31944
WB Predicted band size 28 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human Caspase 14
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
FCM 1/20-1/100
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