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Rabbit Monoclonal to Phospho-Rac1/Cdc42(Ser71)
货号: P17444
别名: CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25;;p-Cdc42/Rac1 (S71)
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P60953/P63000
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Description

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

Specification

Aliases CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25;;p-Cdc42/Rac1 (S71)
Swissprot P60953/P63000
WB Predicted band size Calculated MW: 21 kDa ; Observed MW: 24 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human Cdc42 around the phosphorylation site of S71
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
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