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Mouse Monoclonal Antibody to CCNA2
货号: 30714
别名: CCN1; CCNA
应用: WB,IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P20248
规格:
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Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

References

1. Cancer. 2011 Sep 1;117(17):4080-91.
2. J Phys Chem B. 2008 Jul 17;112(28):8346-53.

Specification

Aliases CCN1; CCNA
Entrez GeneID 890
Swissprot P20248
clone 6B4D11
WB Predicted band size 48.6kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CCNA2 (AA: 105-233) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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