Rabbit Monoclonal to HMGCR
货号:
P17497
别名:
3H3M; HMDH; HMG CoA reductase; HMG CoAR;;HMGCR
应用:
WB;IP
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P04035
规格:
目录价
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Description |
|---|
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs. |
Specification |
|
|---|---|
| Aliases | 3H3M; HMDH; HMG CoA reductase; HMG CoAR;;HMGCR |
| Swissprot | P04035 |
| WB Predicted band size | 97 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human HMGCR |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |




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