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Rabbit Monoclonal to TMEM16A
货号: P17562
别名: Anoctamin-1; ANO1; DOG1; ORAOV2; TAOS2; TMEM16A;;Anoctamin 1
应用: IHC;FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q5XXA6
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Description

Plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Required for CFTR activation by enhancing endoplasmic reticulum Ca2+ store release and is also required for CFTR membrane expression.

Specification

Aliases Anoctamin-1; ANO1; DOG1; ORAOV2; TAOS2; TMEM16A;;Anoctamin 1
Swissprot Q5XXA6
WB Predicted band size 114 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human Anoctamin 1
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

IHC 1/100-1/200
FCM 1/20-1/100

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