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Rabbit Monoclonal to Tyrosinase
货号: P17575
别名: ATN; CMM8; LB24 AB; SHEP3; SK29 AB; Tumor rejection antigen AB; TYR;;Tyrosinase
应用: WB,IHC/IHF,IF,
反应种属: Human
抗体类型: Primary antibody
Swissprot: P14679
规格:
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Description

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.

Specification

Aliases ATN; CMM8; LB24 AB; SHEP3; SK29 AB; Tumor rejection antigen AB; TYR;;Tyrosinase
Swissprot P14679
WB Predicted band size Calculated MW: 60 kDa ; Observed MW: 70-80 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human Tyrosinase
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
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