Rabbit Monoclonal to IRAK
货号：
P17645
别名：
Il1rak; IRAK; Irak1; IRAK1-S; mPLK; Pelle; Pelle homolog; Pelle-like protein kinase; Plpk;;IRAK1
应用：
WB,IF,IP
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P51617
规格：
目录价
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Description |
|---|
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. |
Specification |
|
|---|---|
| Aliases | Il1rak; IRAK; Irak1; IRAK1-S; mPLK; Pelle; Pelle homolog; Pelle-like protein kinase; Plpk;;IRAK1 |
| Swissprot | P51617 |
| WB Predicted band size | 77 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human IRAK1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| IF | 1/50-1/200 |
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