Rabbit Monoclonal to MBD1
货号：
P17661
别名：
CXXC 3; Mbd1; MECP1 COMPLEX; PCM1; RFT;;MBD1
应用：
WB,IHC/IHF,IF,IP
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UIS9
规格：
目录价
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Description |
|---|
Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting ATF7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. |
Specification |
|
|---|---|
| Aliases | CXXC 3; Mbd1; MECP1 COMPLEX; PCM1; RFT;;MBD1 |
| Swissprot | Q9UIS9 |
| WB Predicted band size | 67 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human MBD1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
| IF | 1/50-1/200 |
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