Mouse Monoclonal Antibody to HH3
货号:
30741
别名:
HIST2H3A;H3/n; H3/o
应用:
WB,FCM
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q71DI3
规格:
目录价
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Description |
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. |
References |
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Br J Nutr. 2010 Feb;103(3):344-51. J Biol Chem. 2008 Feb 8;283(6):3006-10. |
Specification |
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Aliases | HIST2H3A;H3/n; H3/o |
Entrez GeneID | 333932 |
Swissprot | Q71DI3 |
clone | 6D3B9 |
WB Predicted band size | 15.4kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide fragment of human HH3 (AA: 121-136) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using HH3 mouse mAb against K562 (1), C6(2),HEK293(3),PC-12(4) and NIH/3T3(5) cell lysate.
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Flow cytometric analysis of NIH/3T3 cells using HH3 mouse mAb (green) and negative control (red).