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Mouse Monoclonal Antibody to HH3
货号: 30741
别名: HIST2H3A;H3/n; H3/o
应用: WB,FCM
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q71DI3
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Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

References

Br J Nutr. 2010 Feb;103(3):344-51.
J Biol Chem. 2008 Feb 8;283(6):3006-10.

Specification

Aliases HIST2H3A;H3/n; H3/o
Entrez GeneID 333932
Swissprot Q71DI3
clone 6D3B9
WB Predicted band size 15.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide fragment of human HH3 (AA: 121-136) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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