Rabbit Monoclonal to FADD
货号：
P17787
别名：
FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1;;Fadd
应用：
WB;IHC;FCM
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q61160(mouse)(human:Q13158)
规格：
目录价
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Description |
|---|
Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
Specification |
|
|---|---|
| Aliases | FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1;;Fadd |
| Swissprot | Q61160(mouse)(human:Q13158) |
| WB Predicted band size | Calculated MW: 23 kDa ; Observed MW: 28 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | A synthesized peptide derived from mouse Fadd |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IHC | 1/100-1/200 |
| FCM | 1/20-1/100 |
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