Rabbit Monoclonal to RNF8
货号:
P17784
别名:
C3HC4 type zinc finger protein; RNF8;;RNF8
应用:
WB
反应种属:
Human,Rat
抗体类型:
Primary antibody
Swissprot:
O76064
规格:
目录价
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Description |
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E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. |
Specification |
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Aliases | C3HC4 type zinc finger protein; RNF8;;RNF8 |
Swissprot | O76064 |
WB Predicted band size | Calculated MW: 56 kDa ; Observed MW: 60 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat |
Immunogen | A synthesized peptide derived from human RNF8 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |