Rabbit Monoclonal to CDT2
货号:
P17846
别名:
CDW1; DCAF2; Dtl; L2DTL; RAMP;;CDT2
应用:
WB,IHC/IHF,IF,FCM
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q9NZJ0
规格:
目录价
在线咨询
Description |
---|
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), FBH1, KMT5A and SDE2. |
Specification |
|
---|---|
Aliases | CDW1; DCAF2; Dtl; L2DTL; RAMP;;CDT2 |
Swissprot | Q9NZJ0 |
WB Predicted band size | Calculated MW: 79 kDa ; Observed MW: 91 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human CDT2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/1000-1/2000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |
FCM | 1/20-1/100 |