Rabbit Monoclonal to HMGCL
货号：
P17938
别名：
HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725;;HMGCL
应用：
WB;IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P35914
规格：
目录价
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Description |
|---|
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. |
Specification |
|
|---|---|
| Aliases | HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725;;HMGCL |
| Swissprot | P35914 |
| WB Predicted band size | Calculated MW: 34 kDa ; Observed MW: 30 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human HMGCL |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IHC | 1/100-1/200 |
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