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Rabbit Monoclonal to Lunatic Fringe
货号: P17982
别名: SCDO3;;LFNG
应用: WB,IF
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q8NES3
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Description

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1.

Specification

Aliases SCDO3;;LFNG
Swissprot Q8NES3
WB Predicted band size 42 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human LFNG
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IF 1/50-1/200
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