Rabbit Monoclonal to CRM1
货号：
P18158
别名：
CRM 1; emb; Exp1; Exportin1; XPO 1;;Exportin 1
应用：
WB,IHC/IHF,IF,FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O14980
规格：
目录价
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Description |
|---|
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. |
Specification |
|
|---|---|
| Aliases | CRM 1; emb; Exp1; Exportin1; XPO 1;;Exportin 1 |
| Swissprot | O14980 |
| WB Predicted band size | Calculated MW: 123 kDa ; Observed MW: 110 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human Exportin 1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
| IF | 1/50-1/200 |
| FCM | 1/20-1/100 |
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