Mouse Monoclonal Antibody to EZR
货号：
30771
别名：
CVL; CVIL; VIL2; HEL-S-105
应用：
WB,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P15311
规格：
目录价
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Description |
|---|
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
References |
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| BMC Cancer. 2013 Nov 4;13:520. Cell Oncol (Dordr). 2013 Dec;36(6):485-91. |
Specification |
|
|---|---|
| Aliases | CVL; CVIL; VIL2; HEL-S-105 |
| Entrez GeneID | 7430 |
| Swissprot | P15311 |
| clone | 6F1C3 |
| WB Predicted band size | 69.4kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human EZR (AA: 292-464) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using EZR mouse mAb against Jurkat (1), A431 (2), MCF-7 (3) and Hela (4) cell lysate.
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Immunofluorescence analysis of Hela cells using EZR mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of A431 cells using EZR mouse mAb (green) and negative control (red).
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