Rabbit Monoclonal to CoREST
货号：
P18152
别名：
COREST; Nr2b2; RCOR; Rcor1; Rxrb;;REST corepressor 1
应用：
WB,IHC/IHF,IF,
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9UKL0
规格：
目录价
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Description |
|---|
Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. |
Specification |
|
|---|---|
| Aliases | COREST; Nr2b2; RCOR; Rcor1; Rxrb;;REST corepressor 1 |
| Swissprot | Q9UKL0 |
| WB Predicted band size | Calculated MW: 53 kDa ; Observed MW: 66 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human REST corepressor 1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
| IF | 1/50-1/200 |
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