Mouse Monoclonal Antibody to MGMT
货号:
30779
别名:
应用:
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P16455
规格:
目录价
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Description |
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MGMT involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated |
References |
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Folia Neuropathol. 2013;51(4):275-82. Fam Cancer. 2013 Sep;12(3):449-58. |
Specification |
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Entrez GeneID | 4255 |
Swissprot | P16455 |
clone | 1A11A8 |
WB Predicted band size | 21.6kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human MGMT (AA: 32-210) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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ELISA | 1/10000 |