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Rabbit Monoclonal to CENPC
货号: P18231
别名: CENP-C; CENPC1; hcp-4; ICEN7; MIF2;;CENPC
应用: WB,IHC/IHF,IF,IP,FCM
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q03188
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Description

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Specification

Aliases CENP-C; CENPC1; hcp-4; ICEN7; MIF2;;CENPC
Swissprot Q03188
WB Predicted band size 107 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human CENPC
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
FCM 1/20-1/100
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