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Rabbit Monoclonal to WNK1
货号: P18273
别名: KDP; PSK; p65; HSN2; HSAN2; PRKWNK1;;WNK1
应用: WB;IHC
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q9H4A3
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Description

Serine/threonine-protein kinase component of the WNK1-SPAK/OSR1 kinase cascade, which acts as a key regulator of blood pressure and regulatory volume increase by promoting ion influx.WNK1 mediates regulatory volume increase in response to hyperosmotic stress by acting as a molecular crowding sensor, which senses cell shrinkage and mediates formation of a membraneless compartment by undergoing liquid-liquid phase separation.

Specification

Aliases KDP; PSK; p65; HSN2; HSAN2; PRKWNK1;;WNK1
Swissprot Q9H4A3
WB Predicted band size 251 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human WNK1
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC 1/100-1/200
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