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Rabbit Monoclonal to KMT1B/SUV39H2
货号: P18253
别名: H3 K9 HMTase 2; KMT1B; Su(var)3 9 homolog 2; Suv39h2;;KMT1B
应用: WB;IHC;IP
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q9H5I1
规格:
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Description

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions.

Specification

Aliases H3 K9 HMTase 2; KMT1B; Su(var)3 9 homolog 2; Suv39h2;;KMT1B
Swissprot Q9H5I1
WB Predicted band size 47 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human KMT1B
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
IHC 1/100-1/200
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