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Rabbit Monoclonal to KAISO
货号: P18368
别名: Kaiso; Zbtb33; ZNF Kaiso; ZNF348;;KAISO
应用: WB
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q86T24
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Description

Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters.

Specification

Aliases Kaiso; Zbtb33; ZNF Kaiso; ZNF348;;KAISO
Swissprot Q86T24
WB Predicted band size Calculated MW: 74 kDa ; Observed MW: 85 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human KAISO
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
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