Rabbit Monoclonal to MBNL1
货号:
P18363
别名:
EXP; EXP35; EXP40; EXP42; MBNL; MBNL1;;MBNL1
应用:
WB
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q9NR56
规格:
目录价
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Description |
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Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. |
Specification |
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Aliases | EXP; EXP35; EXP40; EXP42; MBNL; MBNL1;;MBNL1 |
Swissprot | Q9NR56 |
WB Predicted band size | Calculated MW: 42 kDa ; Observed MW: 40 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | A synthesized peptide derived from human MBNL1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |