Rabbit Monoclonal to TRAP1
货号：
P18399
别名：
HSP75; HSP90L; Trap1;;Hsp75
应用：
WB,IHC/IHF,IF,
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q12931
规格：
目录价
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Description |
|---|
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. |
Specification |
|
|---|---|
| Aliases | HSP75; HSP90L; Trap1;;Hsp75 |
| Swissprot | Q12931 |
| WB Predicted band size | Calculated MW: 80 kDa ; Observed MW: 75 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Hsp75 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
| IF | 1/50-1/200 |
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