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Rabbit Monoclonal to IL23
货号: P18409
别名: IL 23A; IL 23p19; IL12B; IL23; Il23a; IL23P19; P19; SGRF;;IL 23A
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9NPF7
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Description

Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.

Specification

Aliases IL 23A; IL 23p19; IL12B; IL23; Il23a; IL23P19; P19; SGRF;;IL 23A
Swissprot Q9NPF7
WB Predicted band size 21 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human IL 23A
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
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