Rabbit Monoclonal to DARC
货号:
P18390
别名:
CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1;;Atypical chemokine receptor 1
应用:
WB,IHC/IHF,IF,IP,FCM
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q16570
规格:
目录价
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Description |
|---|
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. |
Specification |
|
|---|---|
| Aliases | CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1;;Atypical chemokine receptor 1 |
| Swissprot | Q16570 |
| WB Predicted band size | Calculated MW: 36 kDa ; Observed MW: 35 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | A synthesized peptide derived from human Atypical chemokine receptor 1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
| IF | 1/50-1/200 |
| FCM | 1/20-1/100 |


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