Rabbit Monoclonal to CELF1
货号:
P18563
别名:
BRUNOL2; celf1; CUGBP; CUGBP1; EDEN BP; hNab50; NAB50; NAPOR;;CELF 1
应用:
WB,IHC/IHF,IF,IP,FCM
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q92879
规格:
目录价
在线咨询
Description |
|---|
RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts both as an activator and as a repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB. |
Specification |
|
|---|---|
| Aliases | BRUNOL2; celf1; CUGBP; CUGBP1; EDEN BP; hNab50; NAB50; NAPOR;;CELF 1 |
| Swissprot | Q92879 |
| WB Predicted band size | 52 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human CELF 1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
| IF | 1/50-1/200 |
| FCM | 1/20-1/100 |




鄂公网安备42018502007531号

