Rabbit Monoclonal to PAG
货号：
P18614
别名：
CBP; Csk binding protein; PAG; PAG1;;PAG1
应用：
WB;IHC;IP;FCM
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9NWQ8
规格：
目录价
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Description |
|---|
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling. |
Specification |
|
|---|---|
| Aliases | CBP; Csk binding protein; PAG; PAG1;;PAG1 |
| Swissprot | Q9NWQ8 |
| WB Predicted band size | Calculated MW: 47 kDa ; Observed MW: 80 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human PAG1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| IHC | 1/100-1/200 |
| FCM | 1/20-1/100 |
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