Rabbit Monoclonal to Phospho-Tuberin(T1462)
货号：
P18663
别名：
LAM; PPP1R160; Protein phosphatase 1, regulatory subunit 160; tsc2; TSC4; TSC4, formerly; Tuberin; Tuberous sclerosis 2; ;p-Tuberin (T1462)
应用：
WB;IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P49815
规格：
目录价
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Description |
|---|
Catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth.Within the TSC-TBC complex, TSC2 acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. |
Specification |
|
|---|---|
| Aliases | LAM; PPP1R160; Protein phosphatase 1, regulatory subunit 160; tsc2; TSC4; TSC4, formerly; Tuberin; Tuberous sclerosis 2; ;p-Tuberin (T1462) |
| Swissprot | P49815 |
| WB Predicted band size | Calculated MW: 201 kDa ; Observed MW: 200 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | A synthesized peptide derived from human Tuberin around the phosphorylation site of T1462 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IHC | 1/100-1/200 |
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