Rabbit Monoclonal to Timeless
货号:
P18759
别名:
hTIM; TIM; TIM1; Timeless; timeless circadian clock 1; TIMELESS1;;Timeless
应用:
WB,IHC/IHF,IF,
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9UNS1
规格:
目录价
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Description |
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Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication, DNA repair and in the regulation of the circadian clock.Required to stabilize replication forks during DNA replication by forming a complex with TIPIN: this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. |
Specification |
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Aliases | hTIM; TIM; TIM1; Timeless; timeless circadian clock 1; TIMELESS1;;Timeless |
Swissprot | Q9UNS1 |
WB Predicted band size | Calculated MW: 139 kDa ; Observed MW: 150 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthesized peptide derived from human Timeless |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |