Rabbit Monoclonal to WRN
货号：
P18783
别名：
Exonuclease WRN; RecQ3; RECQL2; RECQL3; Werner syndrome helicase; WRN;;WRN
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q14191
规格：
目录价
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Description |
|---|
Multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions. |
Specification |
|
|---|---|
| Aliases | Exonuclease WRN; RecQ3; RECQL2; RECQL3; Werner syndrome helicase; WRN;;WRN |
| Swissprot | Q14191 |
| WB Predicted band size | Calculated MW: 162 kDa ; Observed MW: 200 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human WRN |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
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